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Spectroscopic Fingerprints of Cavity Formation and Solute Insertion as a Measure of Hydration Entropic Loss and Enthalpic Gain
Angew. Chem. Int. Ed.: RESOLV spokeperson Prof. M. Havenith's study addresses the challenge of distinguishing between hydrophilic and hydrophobic contributions to hydration free energies—an essential step toward a deeper understanding of biological processes. By applying THz calorimetry, the team linked specific THz spectral signatures to group-specific solvation entropy and enthalpy. This…