RESOLV member Prof. Elsa Sanchez-Garcia and a group of researchers present, CLR01 and CLR05 based advanced molecular tweezers that reveal a dual mechanism of action, choline binding and hydrophobic insertion, that underpins the broad-spectrum antiviral activity of advanced molecular tweezers and establish them as a promising new class of membrane-targeting antivirals for prophylactic and…

RESOLV member Prof. Guido Clever's international research team has developed a new class of flexible, metal-based cage molecules capable of simultaneously binding positively and negatively charged guest molecules.

RESOLV member Prof. Simon Ebbinghaus and his team have examined one of these proteins more closely and described its dynamic behavior.

RESOLV members, Prof. Frank Neese and Prof. Benjamin List’s working groups have collaborated to develop a novel reaction that enables the synthesis of stable, open-chain amines with nitrogen chirality. The scientists published their groundbreaking results in Nature.

RESOLV members, Prof. K. Tschulik, Prof. M. Muhler, and Prof. H. Tüysüz have discovered a way to keep a cobalt-based oxide electrocatalyst active and stable.

RESOLV member, Prof. M. M. Hansmann's research group has now been able to investigate the reactivity of C2O using an isolable equivalent in which the C2O is "masked.

J. Org. Chem.: RESOLV member, Prof. Elsa Sánchez-Garcia examines and compares the interactions between two different carbenes with coinage metal surfaces. Carbenes being key intermediates serve an important role in many chemical applications. In this study, the group computationally investigates cyclopentadienylidene (CP), an electrophilic reactive carbene, and it's structurally analogous…

Chem. Rev.: RESOLV members, Prof. Elsa Sánchez-García and Prof. Wolfram Sander delve into the intricate network of intermolecular interactions that govern protein structure and function. This review examines how both strong ionic contacts and weak hydrophobic forces, modulated by solvent effects, influence protein folding, enzymatic activity, and protein–peptide binding. Through computational case…

Angew. Chem. Int. Ed. : RESOLV member Prof. Stefan M. Huber presents the second generation of a bidentate Iodine(I)-based halogen bond donor as a modifiable and highly active chiral halogen bonding catalyst. With these modified derivatives, high stereocontrol of up to 98% ee could be achieved in a model Mukaiyama aldol reaction for a range of different substrates. Importantly, the crucial role of…

Nat. Commun.: RESOLV members Prof. Kai Exner and Prof. Christof Hättig show that oxygen evolution can proceed in a concerted manner, which could be a game-changer for catalyst design in green hydrogen.