PNAS: Researchers from Bochum, led by Prof. T. Happe, and researchers from Osaka have discovered how an extraordinary protein survives in the presence of oxygen.

Angew. Chem. Int. Ed.: RESOLV member, Prof. Dr. Max M. Hansmann presents a novel method to generate room-temperature stable diazoalkenes by cleaving carbophosphinocarbenes and carbodicarbenes with nitrous oxide (N₂O). The work highlights the untapped potential of NHC/N₂ and N₂/L exchange at carbon(0) centers for rapid molecular assembly.

J. Phys. Chem. Lett.: RESOLV member, Prof. André K. Eckhardt presents a novel gas-phase reaction that merges cycloaddition and cross-coupling in a single collision, enabling the in situ formation of aromatic molecules via a radical pathway. Crossed molecular beam experiments and electronic structure calculations reveal the formation of (substituted) arylacetylenes from 1,3-butadiynyl radicals and…

Nat. Chem.: RESOLV ECR group leader Dr. J. Cornellà and RESOLV Principle Investigator Prof. F. Neese and their teams published fascinating findings.

PNAS: In a collaborative study, researchers led by RESOLV scientists, Prof. J. Tatzelt, Prof. K. Winklhofer, and Prof. R. Winter, have gained valuable insight into the development of prion diseases of the brain.

Chem. Eur. J.: Joint publication RESOLV members Prof. K. Morgenstern and Prof. W. Sander. It is well established that the confinement of reactants to two dimensions influences their reactivity. However, such confinement is often dominated by charge transfer effects between the reactants and the confining walls, in particular if the walls are conductive. Also, the reactivity of carbenes on metal…

JACS: Single-atom catalysts combine the advantages of homogeneous and heterogeneous catalysis. Researchers led by Prof. K. Exner have now shown that such structures can also be formed electrochemically – independently and without noble metals. They are highly selective and can be easily separated from the reaction mixture.

Prot. Sci.: Joint publication RESOLV members Prof. P. Petersen and Dr. A. V. Verde. Proteins of obligate halophilic organisms have an unusually high number of acidic amino acids, thought to enable them to function in multimolar KCl environments. Clarifying the molecular scale mechanisms by which this occurs is relevant for biotechnology, to enable enzymatic synthesis of economically important…

J. Mol. Biol.: Joint publication RESOLV members Prof. J. Tatzelt and Prof. K. F. Winklhofer. Several proteins associated with neurodegenerative diseases, such as the mammalian prion protein (PrP), undergo liquid–liquid phase separation (LLPS), which led to the hypothesis that condensates represent precursors in the formation of neurotoxic protein aggregates. However, the mechanisms that trigger…

J. Phys. Chem. Lett.: Joint publication RESOLV members Prof. D. Marx and Prof. J. Behler. Isotopic substitution, which can be realized in both experiment and computer simulations, is a direct approach to assess the role of nuclear quantum effects on the structure and dynamics of matter. However, the impact of nuclear quantum effects on the structure of liquid water as probed in experiment by…