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PhD student Francesco Righetti searches for the thermometers of bacteria. © RUB, Kramer

NEW RNA THERMOMETER

PNAS: The team around RESOLV PS Prof. Franz Narberhaus and their colleagues at Helmholtz Center for Infection Research in Braunschweig and Leipzig University developed a new RNA thermometer.

Using cutting-edge high-throughput sequencing methods, researchers have mapped all RNA structures of a diarrhoeal pathogen at once. In the process, they identified a number of temperature-responsive structures, so-called RNA thermometers. “To date, we only ever discovered individual RNA thermometers following a tedious search, and painstakingly analysed one after the other,” says project manager Prof Dr Franz Narberhaus from Ruhr-Universität Bochum.

 

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