ARE YOU A POSTDOC? WE ARE HIRING!

ARE YOU A POSTDOC? WE ARE HIRING!

Call open: 20 positions within the RESOMUS - EU COFUND Fellowship Programme

RESOLV presents business incubator

RESOLV presents business incubator

NEWS HIGHLIGHT: RESOLV's Speaker Martina Havenith presented Start4Chem to German Chancellor Angela Merkel during her visit in North Rhine-Westphalia .

RUHR EXPLORES SOLVATION SCIENCE

RUHR EXPLORES SOLVATION SCIENCE

We shape a new scientific discipline, inspire the scientists of tomorrow, and enable future technologies

WE ARE RESOLV

WE ARE RESOLV

Over 200 scientists from about 50 research groups in 6 institutions

ZEMOS: Home of Solvation Science @RUB

ZEMOS: Home of Solvation Science @RUB

The first research building for Solvation Science in the world. Hosts over 100 scientists, it's home to 6 disciplines.

WHAT is RESOLV?

The Cluster of Excellence RESOLV is an interdisciplinary research project of the Ruhr University Bochum and the TU Dortmund University, as well as four other institutions in the German Ruhr area. Since 2012, about 200 scientists cooperate to clarify how the solvent is involved in the control, mediation and regulation of chemical reactions. Our research is essential to advance technologies that could reuse CO2 for chemicals production, increase the efficiency of energy conversion and storage and develop smart sensors. RESOLV is funded by the German Federal Government and the state of North Rhine-Westphalia with 42 Mio. EUR over the period 2019-2025. 

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Latest News or browse all

Posted on
Guido Clever and Irene Regeni hold a 3D print of the peanut-like object ©Clever
The peanut-like objects self-assemble into a chain-like object (left, middle). The chain-like structures then aggregate into small discs (middle, red). DNA (green) disaggregates the discs and binds to the chain-like objects in water solution. ©Clever

Peanut-like nano objects self-assemble in solution, bind DNA

Angew. Chem.: Nano objects with spectacular shape and promising functions.

RESOLV chemist Guido Clever has just synthesized two nano objects showing unprecedented structures and properties. One object has two cavities, resembling the shell of a peanut. Another object has a complex chain-like structure and can bind to DNA. 

The role of the solvent in the process is significant: Acetonitrile, a polar solvent, mediates the reaction between the organic components and the metal cations (palladium) involved in the process.The interaction with biomolecules like DNA suggests that these compounds may be used as potential diagnostic or therapeutic tools. The results have been reported as a VIP paper in the renowned journal ‘Angewandte Chemie International Edition’.

Original publication:

R. Zhu, I. Regeni, J. J. Holstein, B. Dittrich, M. Simon, S. Prévost, M. Gradzielski, G. H. Clever: "Catenation and Aggregation of Multy-Cavity Coordination Cages", in: Angew. Chem. Int. Ed. 2018, DOI: 10.1002/anie.201806047

 

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Posted on
Guido Clever and Irene Regeni hold a 3D print of the peanut-like object ©Clever
The peanut-like objects self-assemble into a chain-like object (left, middle). The chain-like structures then aggregate into small discs (middle, red). DNA (green) disaggregates the discs and binds to the chain-like objects in water solution. ©Clever

Peanut-like nano objects self-assemble in solution, bind DNA

Angew. Chem.: Nano objects with spectacular shape and promising functions.

RESOLV chemist Guido Clever has just synthesized two nano objects showing unprecedented structures and properties. One object has two cavities, resembling the shell of a peanut. Another object has a complex chain-like structure and can bind to DNA. 

The role of the solvent in the process is significant: Acetonitrile, a polar solvent, mediates the reaction between the organic components and the metal cations (palladium) involved in the process.The interaction with biomolecules like DNA suggests that these compounds may be used as potential diagnostic or therapeutic tools. The results have been reported as a VIP paper in the renowned journal ‘Angewandte Chemie International Edition’.

Original publication:

R. Zhu, I. Regeni, J. J. Holstein, B. Dittrich, M. Simon, S. Prévost, M. Gradzielski, G. H. Clever: "Catenation and Aggregation of Multy-Cavity Coordination Cages", in: Angew. Chem. Int. Ed. 2018, DOI: 10.1002/anie.201806047

 

read more 

Our scientific fields

Research Area I

Local Solvent Fluctuations in Heterogeneous Systems

 

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Research Area II

Solvent Control of Chemical Dynamics and Reactivity

 

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Research Area III

Solvation under Extreme Conditions

 

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Video: The solvent of life

Water. It’s the most abundant substance on Earth´s surface and in our bodies. But is water a passive spectator in the animated scene of bio-chemical reactions inside our cells? RESOLV scientists investigate the important role that water plays in the most diverse processes, bringing solvation science into the spotlight.

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Upcoming Events or browse all

Posted on
Guido Clever and Irene Regeni hold a 3D print of the peanut-like object ©Clever
The peanut-like objects self-assemble into a chain-like object (left, middle). The chain-like structures then aggregate into small discs (middle, red). DNA (green) disaggregates the discs and binds to the chain-like objects in water solution. ©Clever

Peanut-like nano objects self-assemble in solution, bind DNA

Angew. Chem.: Nano objects with spectacular shape and promising functions.

RESOLV chemist Guido Clever has just synthesized two nano objects showing unprecedented structures and properties. One object has two cavities, resembling the shell of a peanut. Another object has a complex chain-like structure and can bind to DNA. 

The role of the solvent in the process is significant: Acetonitrile, a polar solvent, mediates the reaction between the organic components and the metal cations (palladium) involved in the process.The interaction with biomolecules like DNA suggests that these compounds may be used as potential diagnostic or therapeutic tools. The results have been reported as a VIP paper in the renowned journal ‘Angewandte Chemie International Edition’.

Original publication:

R. Zhu, I. Regeni, J. J. Holstein, B. Dittrich, M. Simon, S. Prévost, M. Gradzielski, G. H. Clever: "Catenation and Aggregation of Multy-Cavity Coordination Cages", in: Angew. Chem. Int. Ed. 2018, DOI: 10.1002/anie.201806047

 

read more 

igss summer school

The integrated Graduate School Solvation Science hosts an annual Summer School at the Ruhr University Bochum. The school always takes place during Whitsuntide and is an integral part of the GSS students' training during their doctoral studies. The seventh Summer School Solvation Science has been cancelled for 2020 due to the current pandemic caused by the virus COVID-19. Stay tuned for updates!

International speakers, suggested by the students themselves, are invited to give keynote talks on their research in the field of Solvation Science. The Advanced Laboratory Modules give the students an excellent opportunity to learn new and interesting experimental and theoretical techniques within a specific research topic of their own choice. 

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Publications highlight

R Schwan, C Qu, D Mani, N Pal L van der Meer, B Redlich, C Leforestier, JM Bowman, G Schwaab, M Havenith
Observation of the Low-Frequency Spectrum of the Water Dimer as a Sensitive Test of the Water Dimer Potential and Dipole Moment Surfaces, Angew. Chem. 58 (2019), DOI: 10.1002/anie.201906048

N Berger, LJB Wollny, P Sokkar, S Mittal, J Mieres-Perez, R Stoll, W Sander, E Sanchez-Garcia
Solvent-Enhanced Conformational Flexibility of Cyclic Tetrapeptides, ChemPhysChem 20 (2019), 1664, DOI: 10.1002/cphc.201900345

A El Arrassi, Z Liu, MV Evers, N Blanc, G Bendt, S Saddeler, D Tetzlaff, D Pohl, C Damm, S Schulz, K Tschulik
Intrinsic Activity of Oxygen Evolution Catalysts Probed at Single CoFe2O4 Nanoparticles, J. Am. Chem. Soc. 141 (2019), 9197, DOI: 10.1021/jacs.9b04516

D Mani, R Pérez de Tudela, R Schwan, N Pal, S Körning, H Forbert, B Redlich, AFG van der Meer, G Schwaab, D Marx, M Havenith
Acid solvation versus dissociation at “stardust conditions”: Reaction sequence matters, Science Advances  5 (2019), eaav8179, DOI: 10.1126/sciadv.aav8179

CAJ Hutter, MH Timachi, LM Hürlimann, I Zimmermann, P Egloff, H Göddeke, S Kucher, S Štefanic, M Karttunen, LV Schäfer, E Bordignon, MA Seeger
The extracellular gate shapes the energy profile of an ABC exporter, Nature Communications 10 (2019), 2260, DOI: 10.1038/s41467-019-09892-6

 

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