
Topic 7
Resolution on a molecular level: Exploring the separation of racemates using chiral halogen bond donors.

About the topic:
Our ultimate goal with this project is the resolution of racemic compound-mixtures using chiral halogen bond (XB) donors as cofactors for crystallization. The work should focus on the modification of existing XB-donors with chiral groups and a possible substrate scope. We previously published some results on co-crystallization using perfluorinated XB-donors.
What they are looking for in students:
Students should generally be experienced in lab work, ideally with experience in synthesis or crystallization.





HOW To Apply
For your application you will need:
- CV with contact details and affiliation (max. 2 pages)
- letter of motivation related to Solvation Science (1 page)
- your research proposal (1 page)
Prerequisites: Current Master and PhD students with expiriences in Natural Sciences, Medical Sciences or related topics of Engineering
Start: 15th November 2022
Deadline: 03rd April 2023
collaborating groups
1. Optimization of glycerol-water mixtures for antifreeze function using spectroscopic screening
2. How to control the solubility of supramolecular compounds
3. Improving molecular recognition by leveraging solvation for next-generation biosensing
4. Understanding and manipulating the interactions of water and lanthanoid-DOTA complexes
5. Polarization at the metal/water interface
6. Ultrafast Vibrational Spectroscopy of Proton Transfer Reactions
8. Femtosecond Time-Resolved Spectroscopy of Ion-Solvation Dynamics at Metal-Electrolyte Interfaces
9. Charge Transfer of Doping of Single Organic Nanoparticles for Energy Storage
10. Influence of Solvent mixtures on esterification reactions
Download
Factsheet
Win A research Stay
Subject: conduct your research proposal
Duration: 3 months
Location: Bochum, Germany and local Ruhr RESOLV partner institutions
Language of instruction: English
Costs: RESOLV sponsors travel and a monthly stipend
Period research stay: choose a time between June 2023 – August 2024